TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability
نویسندگان
چکیده
منابع مشابه
TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability
Induced pluripotent stem cells (iPSCs) have revolutionized the world of regenerative medicine; nevertheless, the exact molecular mechanisms underlying their generation and differentiation remain elusive. Here, we investigated the role of the cell fate determinant TRIM32 in modulating such processes. TRIM32 is essential for the induction of neuronal differentiation of neural stem cells by poly-u...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2015
ISSN: 2045-2322
DOI: 10.1038/srep13456